Terpenes are essential in reducing pain and inflammatory conditions Most terpenes are also found in traditional spices and foods Clinical trials of terpenes are in their infancy. Legalization will accelerate further research into terpenes

Terpenes that struggle with pain


1. Β-Caryophyllene

It is one of the most common terpenes and is found in many cannabis strains. It is also found in cloves and black pepper and is responsible for the spicy woody aroma of these plants.

Preclinical data have shown that this terpene has a beneficial anti-inflammatory and analgesic effect. One study looked at the role of carophylene in relieving capsaicin-induced pain. . The researchers found that karyophyllene was able to reduce pain perception by activating the CB2 receptor. Other studies have shown that this terpene is useful in relieving neuropathic pains such as chronic hyperglycemia and diabetes.


2. Myrcene

In most cannabis strains, myrcene is the dominant terpene. It is also found in large quantities in lemongrass. It produces an odorous, herbal, earthy or musky string scent. The scent is most often accompanied by cannabis or hemp. In addition to the sleeping pill, it also offers strong anti-inflammatory benefits.


3. Linalool

Linalool is the most studied monoterpene in the treatment of pain. A mouse study showed that this terpene reduces hypersensitivity and, consequently, helps treat pain caused by paw edema. Other animal models showed similar results where linalool showed analgesic properties by acting on several receptors, including opioids and adenosine.Linalool has also been shown to be very mild on the skin and can be used to make local painkillers. However, its oral bioavailability is low.


4. Limonene

This terpene is common in citrus-flavored strains such as lemon meringues. The scent was described as citrus, mandarin or turpentine. Expect to find a lot of limonene in the citrus peel.

It is a relatively stable monoterpene used as a dietary supplement or ingredient in cosmetic products. A 2020 study reported that this terpene has analgesic significance. Research has shown the usefulness of this terpene in the treatment of headaches, stomach aches and muscle stiffness. It can also be used to stabilize the nervous system. Another study has shown that limonene has anti-inflammatory benefits that also help treat pain. It does this by inhibiting a few inflammatory molecules. In this way, it may be beneficial in the treatment of arthritis.


5. Pinene

It is an organic terpene that smells of pine. Coniferous trees, pine needles, basil and parsley are also common. Studies have shown that this terpene has anti-inflammatory benefits. It may also be useful in the treatment of neuropathic pain. In an animal model study, pinene was able to reduce bone pain.

The majority of studies with analgesic terpenes are preclinical. But if negotiations on federal legalization begin, clinical evidence for the effectiveness and safety of painkillers is likely to be confirmed or ruled out.


(source:www.cannabistraininguniversity.com )

facts

Terpenes are essential in reducing pain and inflammatory conditions

Most terpenes are also found in traditional spices and foods

Clinical trials of terpenes are in their infancy. Legalization will accelerate further research into terpenes