The endocannabinoid system is involved in regulating various functions of the body, including mood, behavior, appetite, pain, sleep, energy, and more. In addition, the endocannabinoid system is responsible for cell growth and apoptosis.
Because cancer is caused by the proliferation and mutation of abnormal cells, the medicinal cannabinoids found in cannabis oil are known to help kill abnormal cancer cells, especially in the early stages of cancer.
Apoptosis is a natural process in the body in which cells are killed as part of the growth of a particular organism. As mentioned earlier, cancer cells grow in the body as a pathological process because they no longer recognize a signal from the body that stimulates or kills cell growth. As these cells grow and divide, they become more uncontrollable. And because they no longer respond to apoptosis, they tend to accelerate cell proliferation and ignore other signs of "normal cells." Therefore, the endocannabinoid system is an extremely important system in the body as it also helps to modulate cell growth and death.
Because cancer cells proliferate faster than the endocannabinoid system can process, cancer cells penetrate normal tissue and spread throughout the body. This process is known as metastasis.
The endocannabinoid system has two primary receptors. One is the CB1 receptor, which is found primarily in the brain, and the other is the CB2 receptor, which is found primarily in the immune system. THC is an active ingredient in cannabis that binds to CB1 receptors and is responsible for mood, behavior, and other brain functions. On the other hand, CBD blocks CB2 receptors and tells these receptors, if any, that they are harmful to the body.
Activation of the receptor after binding may help the endocannabinoid system in antitumor warning. This means that it inhibits carcinogenesis by inhibiting proliferation, metastasis, and tumor angiogenesis.
Although further claims need to be reviewed to support these claims, the cannabinoids in cannabis oil have undoubtedly helped cancer patients one way or another. Chemotherapy patients also turned to cannabis oil to relieve their post-chemotherapy side effects such as nausea, vomiting, fatigue, inflammation, neuropathic pain, immunosuppression, and anorexia.